It is generally suggested that people with MS get flu vaccinations.

This should be discussed with your health care provider.

For people with MS who get vaccinations, it may be best to avoid the vaccination during an attack and to not get the vaccination at a site where one of the injectable medications (Avonex, Betaseron, Copaxone, or Rebif) was recently injected. For those who get significant flu-like side effects with interferon injections (Avonex, Betaseron, or Rebif), it would be reasonable to avoid getting the flu vaccine on the days that you inject your medication......the vaccination should not be used during the first trimester of pregnancy.......There are also a number of oral antiviral medications that may be helpful for the treatment and, in some cases, prevention of flu. These include amantadine (Symmetrel), rimantadine (Flumadine), oseltamivir (Tamiflu), and zanamivir (Relenza). For people with MS, it may be especially useful to begin treatment with such antiviral medications as the flu can precipitate an exacerbation.......Recently, the FDA approved a nasal vaccine, which is inhaled rather than injected-it contains live virus, it is a special risk to those taking immunosuppresive medications, such as steroids, methotrexate, and Novantrone. Family members of people taking such medications should also avoid the nasal vaccine.Rocky Mountain Multiple Sclerosis Center -CLICK TO READ FULL ARTICLE